When disclosures of domestic violence occur as a result of screening or at any point during participation in a healthy marriage or relationship (HMR) program or activity, an effective response must follow. Screening and assessment for domestic violence by HMR programs has two primary purposes: to ensure that referrals to and participation in marriage and relationship education activities are appropriate, and to identify domestic violence victims who may need referral to support services or additional assistance. This Guide, the last of five in a domestic violence Resource Packet developed for HMR educators and program administrators, helps prepare HMR programs to respond when domestic violence is disclosed or detected, and provides strategies for ensuring that effective referrals to domestic violence services and protections occurs.